Define a goal molecule(s) and starting molecule(s) and solve for a reaction pathway between the two optimizing for fewest number of steps, lowest cost, or least amount of time used. Control which resources to be used for pathway search.

Pathway searcher utilizes resources including:

1. local database of known reactions
2. external reaction databases such as Rhea Db
3. list of chemical reactions defined by rules

to produce best fit series of reactions for specified pathway.

Click on the Metabolic Pathways button then click on one of the common metabolic pathways, OR click on the Pathway Searcher button and select a starting molecule, goal molecule, and method of optimization then click search!

Review generated pathways and provide feedback.

Create a pathway in the Innovate/Solve step above and click Review Pathway. You can then view the controls for approving or rejecting the pathway!

Identify new molecules of a similar class as known molecules to discover different therapeutic effects. A lot of drug discoveries throughout history were "accidental". For example, Minoxidil, trade name Rogaine™, was intended originally as a remedy for hypertension when it was noticed that it caused hair growth. Apply reactions to molecules to anticipate products.

Select a common organic molecule as a starting molecule. Select a reaction to apply to the molecule. Click on the beaker to see the result of the reaction!