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Pathways
My Pathways
2-hydroxypropane-1,2,3-tricarboxylic acid - 2-oxobutanedioic acid
Pathway Summary
Citrate
Oxaloacetate
24:12.06
$18.62 per 1g
25 KJ
Verified By:
Steps:
9
Sources:
Rhea DB, Pathway Calculations
Vendors Used:
Sigma Aldrich
Pathway Steps
Step 1
Citrate
Aconitase
cis-Aconitate
H₂O
24:12.06
$1565000 per 1g
-9 KJ
Verified By:
Unverified
Source:
LocalReaction
Vendor:
My Bio Source
Step 2
cis-Aconitate
H₂O
Aconitase
Isocitrate
24:12.06
$1565000 per 1g
-9 KJ
Verified By:
Unverified
Source:
LocalReaction
Vendor:
My Bio Source
Step 3
Isocitrate
NAD+
Isocitrate dehydrogenase
Oxalosuccinate
NADH
H+
24:12.06
$965000 per 1g
-9 KJ
Verified By:
Unverified
Source:
LocalReaction
Vendor:
My Bio Source
Step 4
Oxalosuccinate
Isocitrate dehydrogenase
α-Ketoglutarate
CO₂
24:12.06
$965000 per 1g
-9 KJ
Verified By:
Unverified
Source:
LocalReaction
Vendor:
My Bio Source
Step 5
α-Ketoglutarate
NAD+
CoA-SH
Alpha-ketoglutarate dehydrogenase
Succinyl-CoA
NADH
H+
CO₂
24:12.06
$960000 per 1g
-9 KJ
Verified By:
Unverified
Source:
LocalReaction
Vendor:
My Bio Source
Step 6
Succinyl-CoA
GDP
Pᵢ
Succinyl-CoA synthetase
Succinate
CoA-SH
GTP
24:12.06
$1660000 per 1g
-9 KJ
Verified By:
Unverified
Source:
LocalReaction
Vendor:
My Bio Source
Step 7
Succinate
Q
Succinate dehydrogenase
Fumarate
QH₂
24:12.06
$1220000 per 1g
-9 KJ
Verified By:
Unverified
Source:
LocalReaction
Vendor:
My Bio Source
Step 8
Fumarate
H₂O
Fumarase
L-Malate
24:12.06
$1405000 per 1g
-9 KJ
Verified By:
Unverified
Source:
LocalReaction
Vendor:
My Bio Source
Step 9
L-Malate
NAD+
Malate dehydrogenase
Oxaloacetate
NADH
H+
24:12.06
$980000 per 1g
-9 KJ
Verified By:
Unverified
Source:
LocalReaction
Vendor:
My Bio Source
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The citric acid cycle – also known as the tricarboxylic acid (TCA) cycle or the Krebs cycle[1][2] – is a series of chemical reactions used by all aerobic organisms to generate energy through the oxidation of acetyl-CoA derived from carbohydrates, fats and proteins into carbon dioxide and chemical energy in the form of adenosine triphosphate.
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